Radioprotective
Radioprotective describes substances or interventions that reduce tissue injury caused by ionizing radiation. The term encompasses chemical radioprotectors, physical shielding, and physiological strategies that lessen acute and late radiation effects. In medicine, radioprotective agents are studied to protect normal tissues during radiotherapy and to mitigate harm from accidental or environmental exposure.
Chemical radioprotectors include amifostine (WR-2721), a prodrug converted to the active thiol WR-1065, which scavenges free
Nonpharmacologic measures include shielding with protective barriers, maintaining distance from the radiation source, and minimizing exposure
Radioprotective research aims to improve the therapeutic ratio in radiotherapy and to protect against accidental exposure