RPOF2

RPOF2, also known as RBM39, is a protein-coding gene. The protein encoded by this gene is a serine/arginine-rich (SR) protein, a class of splicing factors that play critical roles in regulating gene expression. Specifically, RPOF2 is involved in the process of alternative splicing, which allows a single gene to produce multiple protein variants. This variability is essential for the complexity and adaptability of many organisms.

The RPOF2 protein interacts with other splicing factors and components of the spliceosome, the molecular machinery responsible for splicing. Its precise functions are still under investigation, but it is believed to influence the selection of splice sites, thereby determining which exons are included or excluded in the final messenger RNA (mRNA) molecule. Dysregulation of RPOF2 or its associated splicing pathways has been implicated in various diseases, including certain types of cancer. Research into RPOF2 continues to explore its involvement in normal cellular processes and its potential as a therapeutic target. Understanding the intricate mechanisms of RPOF2 is crucial for advancing our knowledge of gene regulation and developing novel treatment strategies for diseases linked to splicing defects.