RNF137

RNF137, also known as Ring Finger Protein 137, is a protein encoded by the RNF137 gene in humans. The RNF137 gene is located on chromosome 15. This protein belongs to the ring finger protein family, which are characterized by the presence of a zinc-finger domain that can bind to zinc ions. These types of proteins are often involved in protein-protein interactions and play roles in various cellular processes, including gene regulation, cell cycle control, and apoptosis.

The precise function of RNF137 in cellular pathways is still an active area of research. However, studies have suggested its involvement in the ubiquitin-proteasome system, a critical cellular mechanism for protein degradation and turnover. Ring finger proteins frequently act as E3 ubiquitin ligases, which are enzymes that tag target proteins with ubiquitin, marking them for degradation by the proteasome. This process is essential for maintaining cellular homeostasis and responding to various stimuli. Alterations in RNF137 expression or function have been implicated in certain diseases, although more research is needed to fully understand these connections.