RING2

RING2, also known as RNF137, is a gene that encodes a protein belonging to the RING-finger protein family. This protein plays a crucial role in the ubiquitin-proteasome system, a cellular pathway responsible for protein degradation. The RING-finger domain is a zinc-binding motif that is often found in E3 ubiquitin ligases, enzymes that attach ubiquitin molecules to target proteins, marking them for degradation.

The RING2 protein has been implicated in various cellular processes, including cell cycle regulation, DNA repair, and apoptosis. Its precise function is still under investigation, but it is believed to act as an E3 ubiquitin ligase, facilitating the ubiquitination of specific substrates. The identification of RING2 has contributed to our understanding of the complex regulatory mechanisms governing protein homeostasis within cells. Further research is ongoing to elucidate the full spectrum of RING2's biological functions and its potential involvement in disease development.