RCC1family

RCC1family refers to a family of proteins that are characterized by the presence of a highly conserved domain known as the RCC1 domain. This domain is approximately 120 amino acids in length and is found in a variety of proteins involved in diverse cellular processes. The name RCC1 itself originates from "Regulator of Chromosome Condensation 1," the first protein identified to possess this domain.

Proteins containing the RCC1 domain are often associated with chromatin regulation, DNA repair, and cell cycle control. The RCC1 domain is thought to be involved in protein-protein interactions and may play a role in protein folding and stability. While the exact functions of RCC1family proteins can vary depending on the specific protein and its cellular context, their common structural feature suggests a shared evolutionary origin and potentially related biological roles.

Examples of proteins that contain RCC1 domains include regulators of guanine nucleotide exchange, which are involved in signaling pathways, and proteins involved in transcription. The study of RCC1family proteins contributes to our understanding of fundamental cellular mechanisms and has implications for research into various diseases, including cancer and developmental disorders. Further research continues to elucidate the specific functions and interactions of individual members of this protein family.