Queuosinemodified
Queuosinemodified refers to a post-transcriptional modification of the queuosine nucleoside, a complex guanine derivative found in the first position of the anticodon of certain transfer RNAs (tRNAs) in bacteria, archaea, and eukaryotes. Specifically, queuosine can undergo further modifications, leading to various forms of queuosine. These modifications are crucial for the proper functioning of the modified tRNAs, particularly in ensuring accurate and efficient translation of the genetic code.
The primary modification of queuosine is often the addition of a mannose residue, forming queuosine-oligosaccharide. Other
The presence and modification of queuosine are essential for the translation of codons that contain uracil