Proteinejas
Proteinejas is a term used in speculative and design-focused discussions of protein engineering to describe a class of modular, programmable enzymes that combine substrate recognition with catalytic activity in a single polypeptide. The concept envisions proteins built from interchangeable domains that can be swapped to alter function without redesigning the whole molecule.
Typical Proteinejas architectures comprise a binding domain, a catalytic or modifying domain, and a linker that
Proteinejas are proposed to operate through induced-fit recognition, where substrate binding triggers a conformational change that
Experimental realization involves recombinant production in bacterial or eukaryotic systems, followed by purification and in vitro
While Proteinejas are mainly described in theoretical and early experimental contexts, they are discussed as potential
See also: protein engineering, modular protein design, enzyme design, biocatalysis.