Primäradhäsion

Primäradhäsion refers to the initial stage of wound healing where the edges of a wound are brought together and held in direct contact. This process is most effective in clean, surgical incisions with minimal tissue loss. The goal of primary adhesion is to promote rapid wound closure and minimize the risk of infection and scarring. It relies on the body's natural ability to form a fibrin clot and then initiate cell migration and proliferation to bridge the gap between the wound edges. Techniques used to achieve primary adhesion include sutures, staples, surgical adhesives, and tapes. Successful primary adhesion leads to primary intention healing, characterized by minimal inflammation, rapid re-epithelialization, and a fine scar. Factors influencing the success of primary adhesion include the health of the patient, the type and condition of the wound, and the technique used for closure. Wounds that are contaminated, have significant tissue loss, or are left open are less likely to achieve primary adhesion and will heal by secondary or tertiary intention.