Priestin

Priestin is a brand name for the drug estradiol valerate, a synthetic estrogen. It is primarily used in hormone replacement therapy (HRT) to alleviate symptoms associated with menopause, such as hot flashes, vaginal dryness, and mood swings. Priestin is also prescribed to treat certain gynecological conditions, including primary ovarian failure and atrophic vaginitis. In some cases, it may be used in gender-affirming hormone therapy for transgender women.

The active ingredient, estradiol valerate, is an ester of estradiol, the most potent and naturally occurring estrogen in the human body. Once administered, estradiol valerate is hydrolyzed to estradiol, which then binds to estrogen receptors in various tissues, mimicking the effects of endogenous estrogen. This hormonal action helps to restore physiological levels of estrogen, thereby relieving deficiency symptoms.

Priestin is typically administered via intramuscular injection. The dosage and frequency of administration depend on the individual's medical condition and response to treatment. It is important that Priestin be prescribed and monitored by a qualified healthcare professional, as with any form of hormone therapy. Potential side effects can include breast tenderness, nausea, headache, and an increased risk of blood clots. Contraindications for its use include a history of blood clots, certain types of cancer, and unexplained vaginal bleeding.