Peririmas

Peririmas is a rare and complex genetic disorder characterized by the absence of the lower limbs, specifically the feet and ankles, from birth. The condition is also known as congenital absence of the lower limbs. It is a form of limb reduction defect, where one or both lower limbs are missing or underdeveloped.

The exact cause of peririmas is not fully understood, but it is believed to be a result of abnormal development of the lower limbs during fetal development. The condition can occur as an isolated defect or as part of a broader syndrome, such as the VACTERL association, which includes vertebral defects, anal atresia, cardiac defects, tracheoesophageal fistula, renal anomalies, and limb defects.

Individuals with peririmas may experience mobility challenges and require the use of assistive devices for mobility. The condition can also have psychological and social implications, as it may affect self-esteem and social interactions.

Treatment for peririmas is primarily supportive and focuses on managing mobility and functional limitations. Physical therapy, prosthetics, and orthotic devices may be used to improve mobility and function. In some cases, surgical interventions may be considered to address associated conditions or to improve mobility.

Peririmas is a rare condition, with an estimated prevalence of less than 1 in 100,000 live births. It is important to note that the information provided here is a general overview and that individual experiences and outcomes may vary.