Perimembranous

Perimembranous refers to a location or characteristic that is situated around or adjacent to a membrane. In biology and medicine, this term is frequently used to describe structures or pathological processes. For example, perimembranous ventricular septal defects are a type of congenital heart defect where a hole exists in the wall separating the ventricles of the heart, specifically in the area near the fibrous skeleton and the membranous portion of the interventricular septum.

The term can also be applied more broadly to describe anatomical relationships. A structure might be considered perimembranous if it lies in close proximity to a cell membrane, a tissue membrane, or a mucous membrane. This positional description is important for understanding the spatial organization of cells, tissues, and organs, and for diagnosing and describing medical conditions. The precise meaning of perimembranous often depends on the specific context within which it is used, such as in cardiac anatomy, cellular biology, or histopathology.