PSCD2

PSCD2, also known as pseudocilium assembly protein 2, is a gene that encodes a protein found in eukaryotic cells. This protein plays a role in the formation and function of cilia, which are small, hair-like appendages that extend from the surface of many cell types. Cilia are involved in a variety of cellular processes, including motility, sensing the environment, and facilitating the movement of fluids and particles.

The PSCD2 protein is thought to be a component of the ciliary basal body, a structure that serves as the foundation for cilia assembly. It interacts with other proteins to ensure the proper organization and growth of the cilium. Disruptions in PSCD2 function have been associated with certain ciliopathies, a group of genetic disorders characterized by defects in ciliary structure or function. These disorders can manifest in a wide range of symptoms affecting multiple organ systems. Research into PSCD2 continues to shed light on the complex mechanisms underlying ciliary biology and the pathogenesis of related diseases.