PLA2G2E

PLA2G2E, also known as phospholipase A2 group IIE, is a gene that encodes a secreted enzyme. This enzyme is a member of the phospholipase A2 superfamily, which are characterized by their ability to hydrolyze ester bonds at the sn-2 position of glycerophospholipids. This enzymatic activity suggests a role in lipid metabolism. The PLA2G2E protein is believed to be secreted into extracellular spaces and may participate in various biological processes. While its precise physiological functions are still under investigation, research indicates potential involvement in inflammatory responses and cell signaling pathways. Studies have also explored its association with certain diseases. The gene is located on human chromosome 1. Expression patterns of PLA2G2E have been observed in various tissues, with varying levels depending on cellular context. Further research is ongoing to fully elucidate the biological significance and potential therapeutic applications of PLA2G2E.