PKAS
pKa is the negative logarithm (base 10) of the acid dissociation constant Ka for the equilibrium HA ⇌ H+ + A−. It provides a quantitative measure of an acid’s strength in a given solvent, most commonly water at 25°C. A smaller pKa indicates a stronger acid, because the equilibrium favors dissociation more strongly.
In practical terms, pKa helps predict the protonation state of a species at a given pH. The
Typical pKa values in water at 25°C span a wide range. Strong inorganic acids have negative pKa
Notes: pKa is solvent-dependent and can differ markedly in nonaqueous media. Measurement methods include acid-base titration
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