PGBD
PGBD refers to a family of DNA transposons found in eukaryotic genomes. These are mobile genetic elements that can copy themselves and insert into new locations within the genome. PGBD elements are characterized by their unique structure and mechanism of transposition. They typically consist of inverted terminal repeats flanking a coding sequence that can encode a protein with DNA-binding and endonuclease activity, essential for their movement.
The transposition of PGBD elements is believed to occur through a cut-and-paste mechanism. The PGBD protein
Studies have identified PGBD elements in a wide range of organisms, including humans, where they are considered