PDZ3

PDZ3 refers to a specific domain within a larger protein. PDZ domains are a class of protein interaction modules characterized by a specific three-dimensional structure, typically consisting of about 90 amino acids. They are involved in mediating protein-protein interactions, often playing a role in scaffolding and signaling pathways. The "3" in PDZ3 indicates it is the third identified or characterized PDZ domain within a particular protein or a member of a specific PDZ domain family.

Proteins containing PDZ domains are diverse and found in many organisms, including humans. These domains are known to bind to short peptide sequences, usually found at the C-terminus of target proteins. This binding specificity allows for the assembly of protein complexes and the regulation of various cellular processes such as cell adhesion, synaptic transmission, and cell polarity.

The specific function of a PDZ3 domain depends heavily on the protein it is part of. Without knowing the particular protein, it is difficult to assign a precise role. However, PDZ domains in general are crucial for organizing cellular architecture and facilitating communication between different cellular components. Research into PDZ domains continues to uncover their importance in health and disease.