OXA48typer
OXA48typer is a bioinformatics tool designed to detect and classify blaOXA-48-like carbapenemase genes from sequencing data. It targets OXA-48-like enzymes, a subset of class D beta-lactamases that contribute to carbapenem resistance in Enterobacterales.
OXA-48-type carbapenemases were first described in Enterobacteriaceae and are now found worldwide in species such as
The tool typically relies on a curated reference database of blaOXA-48-like sequences and uses sequence alignment
OXA48typer can be integrated into whole-genome sequencing pipelines or used with targeted sequencing data to support
Limitations include dependence on data quality and the reference database; novel or highly divergent variants may
See also: OXA-48-like carbapenemases; blaOXA-48; antimicrobial resistance.