OPG

OPG is an acronym that can refer to several distinct terms in science, industry, and governance. The two most common references are Ontario Power Generation, a major Canadian electricity producer, and osteoprotegerin, a secreted protein involved in the regulation of bone metabolism.

Ontario Power Generation (OPG) is a Crown corporation owned by the Government of Ontario that generates a substantial portion of the province's electricity. Formed in the late 1990s during electricity sector reforms, OPG operates nuclear, hydroelectric, and other generation assets, and participates in Ontario's electricity markets and grid reliability efforts.

Osteoprotegerin (OPG) is a secreted glycoprotein that belongs to the tumor necrosis factor receptor superfamily. It acts as a decoy receptor for RANKL (and related ligands), inhibiting osteoclast formation and bone resorption. OPG is produced by osteoblasts and other cell types and is studied as a biomarker and potential therapeutic target in bone and cardiovascular diseases.

Other uses of the acronym exist in different countries and fields, but Ontario Power Generation and osteoprotegerin are among the most widely cited meanings in English-language contexts.