Nup58

Nup58 is a protein that is a component of the nuclear pore complex (NPC). The NPC is a large molecular machine that regulates the transport of molecules between the nucleus and the cytoplasm of eukaryotic cells. Nup58 is a member of the nucleoporin family, which are proteins that make up the NPC. It is a transmembrane protein that is localized to the nuclear envelope and plays a role in the structural integrity and function of the NPC. Nup58 is involved in the regulation of nuclear transport, including the import of proteins and the export of RNA. It interacts with other nucleoporins to form the central channel of the NPC, which is responsible for mediating the passage of molecules. Studies have suggested that Nup58 may also have roles beyond nuclear transport, potentially involving in cellular signaling pathways. Its precise functions are still under investigation, but it is considered an essential component of the NPC.