NeuropixelsSonden

Neuropixels probes are a type of high-density neural probe technology developed by imec and Janelia Research Campus. They are designed to record neural activity from thousands of individual neurons simultaneously across large areas of the brain. These probes feature a linear arrangement of hundreds of recording sites, or electrodes, spaced very closely together, typically 20 micrometers apart. This dense arrangement allows for the detection of action potentials from neurons located at different depths within the neural tissue. The probes are made of a thin, flexible material, allowing for insertion into the brain with minimal damage. Each probe can be equipped with various electrode configurations and lengths to suit different experimental needs. The data generated by Neuropixels probes is massive, requiring sophisticated computational analysis to identify and interpret the firing patterns of individual neurons and neural populations. This technology has revolutionized neuroscience research, enabling unprecedented insights into brain function, neural circuits, and the mechanisms underlying behavior and neurological disorders. They are widely used in animal models for studies ranging from basic sensory processing to complex cognitive functions.