Nekrotiz

Nekrotiz is a term derived from the Greek word "nekros," meaning corpse, and is commonly used in biology and medicine to describe the irreversible death of cells or tissues within a living organism. This process is distinct from apoptosis, which is programmed cell death, as necrosis typically results from external factors such as injury, infection, or lack of oxygen.

When necrosis occurs, cellular membranes lose their integrity, leading to the release of cellular contents into the surrounding environment. This can trigger an inflammatory response, further damaging adjacent healthy tissues. The appearance of necrotic tissue can vary depending on the cause and the type of tissue affected. For instance, coagulative necrosis, often seen in heart attacks, results in firm, opaque tissue. Liquefactive necrosis, common in brain tissue affected by a stroke, leads to a soft, mushy consistency.

Causes of necrosis are diverse and can include physical trauma, chemical exposure, prolonged lack of blood supply (ischemia), and infections by pathogens like bacteria or fungi. Certain medical conditions, such as gangrene, are a form of necrosis. Identifying the cause of necrosis is crucial for determining the appropriate medical treatment, which may involve addressing the underlying cause, removing the necrotic tissue to prevent further complications, and managing the inflammatory response.