NODALActivin
NodalActivin is a proposed synthetic ligand in the transforming growth factor beta (TGF-β) superfamily, developed to combine properties of Nodal and Activin signals. It is typically described as a disulfide-linked chimeric dimer that aims to mimic aspects of both Nodal and Activin A signaling.
Molecular features of NodalActivin are designed to incorporate elements from the Nodal and Activin A sequences,
Biological effects of NodalActivin are discussed in the context of pluripotent and differentiating cells. In pluripotent
Applications and status: NodalActivin is primarily described in theoretical or early-stage research as a tool to