NNDiethylmetatoluamide

NN-diethylmetatoluamide, more correctly N,N-diethyl-m-toluamide, is an organic amide that serves as the main active ingredient in many commercial insect repellents. Its IUPAC name is N,N-diethyl-3-methylbenzamide. Synonyms include N,N-diethyl-m-toluamide and N,N-diethyl-3-methylbenzamide. The compound has the molecular formula C12H17NO and a molecular weight of 191.27 g/mol. Its CAS number is 134-62-3.

DEET, as it is commonly known, was developed for insect-repellent applications in the mid-20th century and has been widely used since the 1950s. It is effective against a broad range of biting insects, including mosquitoes, fleas, and ticks. In consumer products it is used at concentrations typically from 5% to 30%, though higher concentrations exist for specialized uses. The mechanism by which DEET repels insects is not fully understood, but it is believed to interfere with the insects’ olfactory system or host-detection cues.

Safety and environmental information: DEET is considered safe when used according to label directions. Potential side effects include skin irritation or allergic reactions in some individuals. It should not be used on broken skin or on very young children without medical advice; concentrations appropriate for children should be chosen, and products should be applied to exposed skin rather than hands. Environmental concerns include aquatic toxicity; DEET should be disposed of according to local guidelines and products should be kept away from water bodies.

Legal status: DEET is registered and regulated as an effective insect repellent by major health and environmental agencies in many countries, with labeling requirements governing concentration, age restrictions, and application guidance.