MetüülSadenosüülmetioniin

MetüülSadenosüülmetioniin, often abbreviated as SAMe, is a naturally occurring compound found in the body. It is synthesized from the amino acid methionine and adenosine triphosphate (ATP). SAMe plays a crucial role in numerous biochemical reactions, particularly in methylation processes. Methylation is a process where a methyl group is transferred from one molecule to another, which is essential for a wide range of cellular functions.

These functions include the synthesis of neurotransmitters like serotonin and dopamine, the production of DNA and RNA, and the metabolism of hormones. SAMe is involved in the synthesis of creatine, carnitine, and phospholipids, which are vital components of cell membranes. Due to its involvement in these essential pathways, SAMe has been studied for its potential therapeutic applications.

Research has explored SAMe's use in conditions such as depression, osteoarthritis, and liver disease. Its proposed mechanisms of action include enhancing neurotransmitter synthesis, providing methyl groups for cellular repair, and exhibiting anti-inflammatory properties. SAMe is available as a dietary supplement and is often taken orally. The body's production of SAMe can be influenced by nutritional status and age.