Mannóz6foszfát
Mannóz6foszfát, also known as mannose-6-phosphate or M6P, is a phosphorylated sugar molecule. It is a key intermediate in the metabolism of mannose. In eukaryotic cells, M6P plays a crucial role in the sorting and trafficking of proteins, particularly lysosomal enzymes.
The synthesis of M6P occurs in the Golgi apparatus. Mannose residues on newly synthesized proteins destined
These M6P receptors bind to the M6P-tagged proteins and direct them to the late endosomes, which eventually