MHCInivåer

MHCInivåer refers to the levels of Major Histocompatibility Complex (MHC) molecules found on the surface of cells. MHC molecules are crucial components of the adaptive immune system, acting as a platform for presenting foreign antigens to T cells. There are two main classes of MHC molecules: MHC class I and MHC class II. MHC class I molecules are expressed on almost all nucleated cells and primarily present intracellular antigens, such as viral proteins or tumor antigens, to cytotoxic T lymphocytes (CTLs). MHC class II molecules are mainly found on professional antigen-presenting cells (APCs) like dendritic cells, macrophages, and B cells. They present extracellular antigens, which have been taken up by the APC, to helper T lymphocytes. Variations in MHCInivåer can occur due to genetic factors, infections, or inflammatory conditions. For instance, increased MHCInivåer can be a sign of immune activation, while decreased levels might impair the immune response. Monitoring MHCInivåer can therefore be a valuable diagnostic tool in certain medical contexts, aiding in the assessment of immune status and disease progression. The specific molecules within the MHC complex are highly polymorphic, meaning there are many different alleles in the population, contributing to the diversity of immune responses.