Lääkeainetasojen

Lääkeainetasojen, also known as drug levels or therapeutic drug monitoring (TDM), refers to the measurement of the concentration of a specific medication in a patient's blood or plasma. This practice is employed for certain medications that have a narrow therapeutic index, meaning the difference between an effective dose and a toxic dose is small. By monitoring these levels, healthcare professionals can ensure that the drug concentration remains within the desired therapeutic range, optimizing efficacy while minimizing the risk of adverse effects.

The decision to monitor drug levels is typically based on factors such as the drug's pharmacokinetic properties, the patient's individual characteristics (e.g., age, weight, organ function), and the presence of clinical signs of toxicity or sub-therapeutic response. Regular monitoring allows for dose adjustments, ensuring that the patient receives the most effective and safest treatment. This is particularly important for medications with variable absorption, metabolism, or excretion, or in patients with conditions that might alter these processes.

Commonly monitored drugs include certain antibiotics, antiepileptics, immunosuppressants, and cardiac medications. The results of drug level measurements, combined with clinical assessment, guide treatment decisions, helping to achieve optimal patient outcomes and prevent potential harm.