Laldostérone

Laldostérone is not listed as a recognized chemical or hormone in standard databases. The term may be a misspelling or a nonstandard variant of aldosterone (aldostérone in French). There is no separate, widely accepted entity by that name. For a related topic, the following describes aldosterone.

Aldosterone is a mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in mammals. It is part of the renin-angiotensin-aldosterone system and regulates electrolyte and fluid balance.

The principal effect of aldosterone is to increase sodium reabsorption in the distal tubules and collecting ducts of the kidney, with a concomitant increase in potassium and hydrogen ion excretion. This promotes an increase in extracellular fluid volume and blood pressure. Aldosterone acts by binding to intracellular mineralocorticoid receptors, altering gene transcription, including that of epithelial sodium channels (ENaC) and Na+/K+-ATPase.

Regulation of aldosterone secretion is primarily through the renin-angiotensin system and plasma potassium levels, with ACTH providing a minor permissive effect. Clinically, hyperaldosteronism causes hypertension and hypokalemia, while hypoaldosteronism can lead to hyperkalemia and metabolic acidosis. Treatments include mineralocorticoid receptor antagonists (such as spironolactone or eplerenone) and, for unilateral adrenal abnormalities, surgical removal. Diagnosis typically involves measurements of plasma aldosterone concentration and plasma renin activity.

If laldostérone refers to aldosterone, the above summarizes the current understanding of the hormone. If it denotes a distinct, fictional term, no established biomedical definition exists in credible sources.