LC3pathway
The LC3 pathway, also known as the microtubule-associated protein 1 light chain 3 (LC3) pathway, is a crucial process in autophagy, a cellular degradation system that maintains cellular homeostasis by removing damaged organelles, aggregates of misfolded proteins, and other unwanted cellular components. Autophagy plays a vital role in various physiological processes, including development, growth, and immune response, and is also involved in the pathogenesis of several diseases, such as neurodegenerative disorders and cancer.
The LC3 pathway is initiated by the formation of a phagophore, a double-membraned structure that expands and
The LC3 pathway is regulated by several factors, including the class III PI3K complex, which generates phosphatidylinositol
The LC3 pathway is a well-studied process, and its components have been extensively characterized. However, the