KunTransfac

KunTransfac is a database that provides information on transcription factors (TFs) and their binding sites in the human genome. It is maintained by the Kunming Institute of Zoology, Chinese Academy of Sciences, and is freely accessible to the scientific community. The database is named after the Kunming region in China, where the institute is located.

KunTransfac contains data on TFs that are known to bind to specific DNA sequences, known as transcription factor binding sites (TFBSs). The database includes information on the TFs themselves, such as their names, aliases, and functions, as well as the TFBSs they recognize. The TFBSs are represented as position weight matrices (PWMs), which describe the probability of each nucleotide occurring at each position in the binding site.

The database also provides tools for searching and analyzing TFBSs. Users can search for TFs by name or function, and for TFBSs by sequence or PWM. The database also includes tools for visualizing TFBSs and for predicting the binding of TFs to DNA sequences.

KunTransfac is updated regularly to include new TFs and TFBSs as they are discovered. The database is a valuable resource for researchers studying gene regulation, as it provides a comprehensive and up-to-date resource for information on TFs and their binding sites.