Komplementtijärjestelmän
The Komplementtijärjestelmän, or complement system, is a part of the innate immune system composed of a series of plasma proteins that cooperate to defend the body against pathogens. These proteins circulate in an inactive form and become activated in a cascade of proteolytic cleavages.
When a pathogen enters the bloodstream, factors in the complement system are triggered by three main pathways:
C3b acts as an opsonin, coating the surface of foreign cells and marking them for phagocytosis by
Regulation of the complement system is crucial to prevent host damage. A number of regulatory proteins, such