Koactivator

Koactivator is a term used in the field of biochemistry and molecular biology to describe a molecule that activates a protein by binding to it. Unlike activators, which typically bind to the active site of an enzyme and directly participate in the catalytic reaction, koactivators bind to a separate site on the protein, often an allosteric site. This binding induces a conformational change in the protein, which in turn activates its function. Koactivators can be small molecules, peptides, or proteins, and their binding can enhance the activity of various types of proteins, including enzymes, receptors, and transcription factors. The mechanism of action of koactivators is crucial in understanding the regulation of cellular processes and is a subject of ongoing research in the field of molecular biology.