Klinisesti

klinisesti is a term used in medical language to denote actions, observations, or conclusions made in a clinical setting. In languages such as Estonian and Finnish, the word translates roughly as “in a clinical manner” or “from a clinical perspective,” emphasizing patient-centered assessment rather than experimental or laboratory conditions.

In practice, statements described as klinisesti refer to real-world patient care: diagnostic reasoning based on symptoms, physical examination, patient history, and imaging interpreted in the context of the individual, as well as decisions about treatment or management. The term is commonly used in clinical notes, case discussions, and guidelines to distinguish everyday medical practice from research conducted outside a clinical environment.

In clinical research, the adverb is used to separate findings that apply to patient care from those obtained in preclinical models. Results described as clinically relevant or clinically meaningful focus on outcomes that matter to patients, such as symptom relief, functional improvement, quality of life, or safety. This contrasts with laboratory or mechanistic results that may advance understanding without immediate implications for patient management.

Relation to clinical significance: while statistical significance concerns the probability that an observed effect is not due to chance, clinically meaningful effects are judged by their practical impact on health and daily living. A result can be statistically significant without being klinisesti or clinically meaningful, and vice versa.