Kalmodulinrelated
Kalmodulinrelated is a term that refers to proteins that share structural or functional similarities with calmodulin, a ubiquitous calcium-binding protein. Calmodulin itself is a key regulator of numerous cellular processes, acting as a calcium sensor that, upon binding calcium ions, undergoes a conformational change. This change allows it to interact with and modulate the activity of a wide array of target proteins, including enzymes, ion channels, and contractile proteins.
Proteins categorized as kalmodulinrelated often possess conserved calcium-binding motifs, typically EF-hand domains, which are characteristic of
The study of kalmodulinrelated proteins is crucial for understanding the intricate regulatory networks within cells. By