Jyseleca

Jyseleca is the brand name for the drug filgotinib. It is a prescription medication used to treat adults with moderately to severely active ulcerative colitis who have had an inadequate response with, lost responsiveness to, or were intolerant to conventional therapy or a biologic agent. It is also approved for the treatment of rheumatoid arthritis in some regions.

Filgotinib belongs to a class of drugs called Janus kinase (JAK) inhibitors. Specifically, it is a selective inhibitor of JAK1. JAK enzymes are involved in signaling pathways that regulate immune responses and inflammation. By inhibiting JAK1, filgotinib helps to reduce the inflammation associated with certain autoimmune conditions like ulcerative colitis and rheumatoid arthritis.

The typical dosage of Jyseleca is determined by a healthcare professional and depends on the severity of the condition being treated. It is usually taken orally once a day. It is important to take Jyseleca exactly as prescribed by your doctor and to inform them of any other medications or supplements you are taking.

Like all medications, Jyseleca can cause side effects. Common side effects may include upper respiratory tract infections, headache, and nausea. More serious side effects can occur, such as an increased risk of serious infections, blood clots, heart attack, stroke, and certain types of cancer. Patients should discuss the potential risks and benefits of Jyseleca with their doctor. Regular monitoring by a healthcare provider is essential while taking this medication.

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