Inotropics

Inotropics are a class of drugs that affect the force of contraction of the heart muscle. They are used to treat heart failure, arrhythmias, and other cardiac conditions. Inotropics work by increasing the amount of calcium available inside the heart muscle cells, which triggers a stronger contraction. There are several types of inotropics, including:

1. Positive inotropics: These drugs increase the force of heart contraction. Examples include dobutamine, milrinone, and levosimendan.

2. Negative inotropics: These drugs decrease the force of heart contraction. Examples include beta-blockers and calcium channel blockers.

3. Neutral inotropics: These drugs do not significantly affect the force of heart contraction but may have other beneficial effects on the heart. Examples include digoxin and spironolactone.

Inotropics are typically administered intravenously and have a short duration of action. They are often used in combination with other medications to manage cardiac conditions. However, they can also have side effects, such as increased heart rate, arrhythmias, and fluid retention. Therefore, they should be used under the supervision of a healthcare professional.