Indometasiini

Indometasiini is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, particularly inflammatory pain, and associated symptoms. It is a propionic acid derivative and works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins.

Indometasiini is available in various forms, including tablets, suppositories, and intravenous solutions. The tablets are available in different strengths, ranging from 25 to 100 mg. Suppositories are typically used for rectal administration.

It is used to treat various conditions, including:

Rheumatoid arthritis: to reduce pain, stiffness, and inflammation

Osteoarthritis: to reduce pain and stiffness

Gout: to reduce pain and inflammation

Enterritis: to reduce pain, inflammation, and other symptoms

Common side effects of indometasiini include gastrointestinal symptoms, such as stomach pain, nausea, and diarrhea. It can also cause allergic reactions, such as hives and itching. Rare but serious potential side effects include:

Kidney damage

Increased risk of heart attack and stroke

Indometasiini should be used with caution in patients with a history of gastrointestinal bleeding, kidney disease, or heart disease. It is available by prescription only. Doses should be adjusted based on individual tolerance and the severity of symptoms.

Long-term use of indometasiini may increase the risk of gastrointestinal damage and other complications. It is recommended to use the lowest effective dose for the shortest duration necessary to achieve the desired therapeutic effect.