Immunosuppressant
Immunosuppressants are medications that dampen or suppress the immune system. They are used primarily to prevent transplant rejection and to treat autoimmune and inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, psoriasis, and certain dermatologic conditions. They also help prevent or treat graft-versus-host disease after hematopoietic stem cell transplantation.
Most immunosuppressants work by interfering with T-cell activation or proliferation, or by reducing immune cell function
Treatment requires careful monitoring. Dosing is individualized and often adjusted based on drug levels, blood counts,
Immunosuppressants have dramatically improved transplant survival and outcomes in autoimmune diseases, but they are not curative