IL15Rtargeted
IL15Rtargeted refers to a class of drugs that specifically target the interleukin-15 receptor (IL-15R). Interleukin-15 is a cytokine that plays a crucial role in the immune system, particularly in the activation and maintenance of natural killer (NK) cells and T cells. The IL-15R is a receptor on the surface of these immune cells that binds to IL-15, initiating a signaling cascade that enhances their cytotoxic activity.
IL15Rtargeted drugs are designed to modulate the immune response by either enhancing or inhibiting the interaction
1. Inhibiting the binding of IL-15 to its receptor, thereby reducing the activation of immune cells.
2. Enhancing the signaling pathway downstream of the IL-15R, leading to increased immune cell activity.
3. Targeting specific components of the IL-15R signaling pathway to achieve a more precise modulation of the
These drugs have shown promise in various therapeutic areas, including cancer, autoimmune diseases, and infectious diseases.
However, like any therapeutic approach, IL15Rtargeted drugs come with their own set of challenges and considerations.