IFN2b

IFN2b, also known as Interferon 2b, is a protein that belongs to the type II interferon family. It is encoded by the IFNA21 gene in humans. Interferons are a group of cytokines that play a crucial role in the immune system's response to viral infections. IFN2b is one of the many subtypes of type II interferons, which are characterized by their ability to bind to the IFNAR1 and IFNAR2 receptors.

IFN2b is primarily expressed in immune cells, such as natural killer cells, T cells, and dendritic cells. Its production is induced by viral infections, and it acts as a signaling molecule to activate the host's immune response. Upon binding to its receptors, IFN2b triggers a cascade of intracellular events that lead to the activation of various genes involved in antiviral defense, such as the production of antiviral proteins and the induction of the interferon-stimulated genes (ISGs).

IFN2b has been studied for its potential therapeutic applications, particularly in the treatment of viral infections. Its ability to activate the immune system and induce antiviral responses makes it a promising candidate for the development of antiviral therapies. However, the use of IFN2b in clinical settings is still limited due to its potential side effects and the need for further research to optimize its therapeutic potential.