HEN2s
HEN2s refers to a family of enzymes involved in DNA repair and replication in eukaryotes. These proteins are also known as HMG-box domain-containing proteins. The HEN2s family typically consists of multiple members within a given organism, each with potentially distinct but overlapping functions. A key feature of HEN2s is the presence of a High Mobility Group (HMG) box domain, which is a DNA-binding motif. This domain allows HEN2s to interact with DNA, often in a sequence-independent manner, by binding to distorted or bent DNA structures.
The primary roles of HEN2s are multifaceted. They are crucial for maintaining genomic stability by participating