Guanidiinkloriid

Guanidiinkloriid, also known as guanidine hydrochloride, is an organic compound with the chemical formula CCl3N3H6. It is a white crystalline solid and is highly soluble in water. Guanidiinkloriid is a strong chaotropic agent, meaning it can disrupt the hydrogen bonding network of water and denature proteins. This property makes it useful in biochemical research for solubilizing proteins and breaking down protein aggregates. It is often used in laboratory settings for protein unfolding and refolding experiments.

The synthesis of guanidiinkloriid typically involves the reaction of dicyandiamide with ammonium chloride. It is also a salt of the strong base guanidine. Beyond its research applications, guanidiinkloriid has found some industrial uses, though these are less common. It can be employed in the production of certain plastics and as a component in some industrial cleaning agents. Its denaturing capabilities are the basis for many of its applications. It is important to handle guanidiinkloriid with care, as it can be irritating to the skin and eyes.