GtRNAdb

GtRNAdb (Genome tRNA Database) is a comprehensive repository of transfer RNA genes annotated in published genomes and organellar genomes. It brings together predicted tRNA genes from a wide range of organisms to facilitate comparative analyses of tRNA gene content, structure, and evolution. The database supports researchers in molecular biology, genomics, and evolutionary biology by providing standardized tRNA gene annotations and related metadata.

Entries in GtRNAdb are generated using established tRNA gene prediction tools, with tRNAscan-SE serving as the core predictor and supplemented by additional analyses and curation. For each tRNA gene, the database records genomic coordinates, anticodon, amino acid isotype, intron status when applicable, gene sequence, and links to the source genome assembly. The resource also flags unusual features and provides indications of potential pseudogenes or derived tRNA candidates where relevant.

Access to GtRNAdb is via a web interface that supports search and browse by organism, anticodon, isotype, or genomic location. Individual tRNA gene records include sequence, structural features, and links to the corresponding genome. Users can download data in common formats for downstream analyses and perform cross-species comparisons of tRNA gene content and copy number.

GtRNAdb covers bacteria, archaea, and eukaryotes, with separate entries for organellar genomes such as mitochondria and chloroplasts. The database is maintained as a long‑term resource and updated as new genome assemblies become available, supporting research into tRNA evolution, codon usage, and genome organization.

See also: tRNAdb, tRNA gene, tRNAscan-SE. External link: gtrnadb.org