GluR1GluR4

GluR1GluR4 refers to a heteromeric ionotropic glutamate receptor composed of GluR1 and GluR4 subunits. This receptor is a member of the ionotropic glutamate receptor family, which plays a crucial role in fast synaptic transmission in the central nervous system. The GluR1GluR4 receptor is primarily expressed in the hippocampus and is involved in learning and memory processes. It is also found in the retina and is involved in visual processing. The GluR1GluR4 receptor is permeable to sodium and calcium ions, and its activation leads to an influx of these ions, resulting in depolarization of the postsynaptic membrane. This receptor is modulated by various neurotransmitters and is a target for several drugs used in the treatment of neurological disorders. The GluR1GluR4 receptor is a heteromeric receptor, meaning it is composed of multiple subunits, with GluR1 and GluR4 being the primary subunits in this specific receptor. The GluR1 subunit is responsible for the binding of glutamate, while the GluR4 subunit is responsible for the regulation of the receptor's function. The GluR1GluR4 receptor is a target for several drugs used in the treatment of neurological disorders, including epilepsy and Alzheimer's disease.