GluK15

GluK15 is not an officially recognized kainate receptor subunit. There is no gene or protein publicly annotated as “GluK15” in major databases such as HGNC or UniProt. The standard nomenclature for kainate receptor subunits uses GluK1–GluK5, encoded by the genes GRIK1, GRIK2, GRIK3, GRIK4, and GRIK5.

If GluK15 appears in some resources, it is likely a misnomer, typographical error, or an informal alias for an existing subunit or a historical naming variation that has not been adopted in current classifications. There is no verified evidence in the literature of a distinct subunit designated GluK15 with its own gene, protein sequence, or functional properties.

Kainate receptors are ionotropic glutamate receptors that form tetrameric channels in the central nervous system. Each subunit has an extracellular amino-terminal domain, a ligand-binding domain, and a transmembrane channel with four segments (M1–M4). They can assemble as homo- or heteromeric receptors, contributing to fast excitatory synaptic transmission and modulating neurotransmission and plasticity. Subunit composition affects pharmacology, kinetics, and trafficking, with distinct expression patterns across brain regions.

Because no validated entry for GluK15 exists, there are no organism-specific expression data, pathogenetic associations, or pharmacological profiles to report for this label. In summary, GluK15 is not recognized as a separate kainate receptor subunit in current scientific references; any reference to it should be cross-checked against established subunits GRIK1–GRIK5.