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GluA4

GluA4 is a subunit of the AMPA receptor, a type of glutamate receptor found in the nervous system. AMPA receptors are ionotropic glutamate receptors, which are a subclass of glutamate receptors that are directly coupled to ion channels. GluA4 is the fourth of seven subunits that can compose the AMPA receptor complex.

The GluA4 subunit is encoded by the GRIA4 gene in humans. It is part of the AMPA

The GluA4 subunit is involved in the regulation of excitatory neurotransmission and has been implicated in

The study of the GluA4 subunit has important implications for understanding the neural mechanisms underlying various

receptor
family,
which
also
includes
GluA1,
GluA2,
GluA3,
GluA5,
GluA6,
and
GluA7.
The
GluA4
subunit
has
a
higher
affinity
for
glutamate
than
other
AMPA
receptor
subunits,
making
it
more
suitable
for
synaptic
transmission
in
the
central
nervous
system.
the
pathophysiology
of
numerous
neurological
and
psychiatric
disorders,
including
Alzheimer's
disease,
epilepsy,
and
schizophrenia.
Studies
have
shown
that
alterations
in
the
expression
and
function
of
the
GluA4
subunit
may
contribute
to
the
development
and
progression
of
these
disorders.
neurological
and
psychiatric
conditions.
Research
has
focused
on
identifying
specific
functional
and
regulatory
properties
of
the
GluA4
subunit
that
could
have
therapeutic
potential.
Further
studies
are
needed
to
explore
the
potential
applications
of
this
knowledge
in
developing
new
treatments
for
these
conditions.