GHKvergelijking
The Goldman-Hodgkin-Katz (GHK) equation is a fundamental relation in physiology that describes the resting membrane potential by accounting for multiple permeant ions and their concentrations and permeabilities across the cell membrane. It generalizes the Nernst equation, which applies to a single ion, to a membrane with several permeant species.
For a cell membrane with permeabilities P_K, P_Na, and P_Cl and extracellular and intracellular concentrations [K+]_o,
The equation relies on the constant-field (uniform electric) assumption and assumes permeabilities are constant in time,
Applications include estimating resting potentials in neurons and other cells and interpreting how changes in ion
See also Nernst equation and the broader concept of membrane potential.