GATAperheens
GATAperheens refers to a family of transcription factors that play a crucial role in cell differentiation and development across a wide range of organisms. These proteins are characterized by a highly conserved DNA-binding domain, known as the GATA zinc finger. This domain allows GATA factors to bind to specific DNA sequences, typically containing the consensus motif WGATAR, where W represents an adenine or thymine and R represents a purine.
The GATA family is a conserved group of transcription factors found in metazoans, with distinct members often
Dysregulation of GATAperheens has been implicated in various diseases. Mutations in GATA1, for example, can lead