GAPproteiinit
GAPproteiinit, also known as GTPases, are a superfamily of enzymes that catalyze the hydrolysis of guanosine triphosphate (GTP) to guanosine diphosphate (GDP) and inorganic phosphate. This seemingly simple enzymatic reaction is central to a vast array of cellular processes. The binding and hydrolysis of GTP by GAP proteins act as a molecular switch, cycling between an active, GTP-bound state and an inactive, GDP-bound state. This conformational change allows them to regulate downstream signaling pathways.
GAP proteins are involved in diverse cellular functions, including signal transduction, protein synthesis, intracellular transport, and
Dysregulation of GAP protein activity has been implicated in various diseases, including cancer, developmental disorders, and