GABAAreseptori
GABAAreseptori, also known as GABA-A receptors, are ligand-gated ion channels that play a crucial role in the central nervous system of vertebrates. They are the principal mediators of inhibitory neurotransmission, primarily by responding to the neurotransmitter gamma-aminobutyric acid (GABA). When GABA binds to its receptor, it causes the channel to open, allowing chloride ions to flow into the neuron. This influx of negative charge hyperpolarizes the neuron, making it less likely to fire an action potential.
These receptors are pentameric structures, meaning they are composed of five protein subunits arranged around a
GABAA receptors are widely distributed throughout the brain and spinal cord. They are found on both excitatory